A modest Midwesterner who became one of the most influential geneticists of the first half of the 20th century, William E. Castle spent his career at Harvard and the University of California working on patterns of inheritance in mice, horses, and a variety of other mammalian taxa. An early proponent of Mendelian theory, Castle was director of the Bussey Institution at Harvard for almost thirty years, helping to train a number of important geneticists. The Castle Papers contain one linear foot of correspondence dating primarily from the period after Castle's "retirement" to Berkeley in 1936 until his death in 1962, dealing almost exclusively with his research on horse breeding and the inheritance of coat coloration in horses. Castle's correspondence with his former student L. C. Dunn is an exception, focusing on mouse genetics and ranging to a variety of topics from the conduct of scientific research during the Second World War to Castle's interests in the early history of genetics.

In 1929, the geneticist C. C. Little founded the Roscoe B. Jackson Memorial Laboratory in Bar Harbor, Maine, a major center for the study of mammalian genetics, cancer, and related areas in basic biomedical research. An independent institution, the Lab has maintained a consistent scientific reputation both as a supplier of inbred strains of mice for genetic and biomedical research and for the scientific achievements of its researchers. Conducted by Susan Mehrtens in 1986, the Oral History Collection includes transcripts of extensive interviews with fifty scientists, administrators, and staff members of the Jackson Laboratory. At greater or lesser length depending on the subject, the interviews provide a detailed picture of the operations and administration at the laboratory, the culture of research, the sometimes contentious staff relations, and the research itself.

Consisting of photocopies of letters written by the geneticists Erwin Baur and Leonard Doncaster to their British colleague William Bateson (1861-1926), the Bateson Collection contains important material relating to the early history of Mendelian genetics in Britain and particularly to Bateson's opposition to the chromosomal theory of inheritance. The originals are held in the William Bateson Papers in the Archives of the John Innes Horticultural Institute.

In addition to correspondence relating to poultry genetics and egg production, there are significant notes concerning breeding records, heredity, and race genetics. There are 42 class notebooks kept by Goodale, and 62 volumes of Mount Hope Poultry Farm family, hatching, mating records for the period 1918 to 1956. The collection includes photographs, glass-lantern lecture slides, and artifacts of poultry feathers.

Ernst Wolfgang Caspari was an important contributor to behavior and developmental genetics, working primarily on the mealmoth Ephestia. Trained in Alfred Kuhn's laboratory at the University of Göttingen (1933-1935), Caspari was forced from his position by the Nazis in 1933, escaping to the United States five years later. As a professor of biology at Lafayette College, Wesleyan University, and the University of Rochester, Caspari continued his research on Ephestia, mouse genetics, and behavior genetics until his retirement in 1975. The Caspari Papers includes correspondence, papers, grant reports, and lectures relating to Caspari's genetic research dating primarily from the period after his departure from Germany. In addition to substantial material on behavior genetics and human evolution, the collection includes correspondence relating to Caspari's editorial work for Advances in Genetics, and his involvement with the American Institute of Biological Sciences, the Center for Advanced Study in the Behavioral Sciences, Cold Spring Harbor Laboratory, Fifth Banff Conference on Theoretical Psychology, Genetics Society of America, International Conference on the Unity of Science, Social Science Research Council, Committee on Genetics and Behavior, and the U.S. Atomic Energy Commission.

L.C. Dunn was one of the most significant figures in the emerging field of developmental genetics in the 20th century. His T-locus work with the mouse established a number of important genetic principles, including ideas of gene interaction, the distribution of alleles in wild populations, and the factors that influence fertility. He wrote an important textbook of genetics, Principles of Genetics (1925), in collaboration with Sinnott (and later Dobzhansky); other significant books authored or co-authored by him include Heredity, Race and Society (1946), and A Short History of Genetics (1965). He worked in poultry genetics for eight years at the Agricultural Experiment Station in Storrs, CT, from 1920-1928. The remainder of his career was spent at Columbia University, where he worked with rats, mice, and fruit flies, and proved himself to be an inspiring teacher as well. His interest in international scientific collaboration led him to establish ties to Soviet scientists, and to help relocate refugee scientists during World War II. He remained active in his profession to the end of his life. This collection includes correspondence, reports, notebooks, lectures, and photographs. It is a rich collection, documenting the development of American genetics as well as Dunn's interests in humanitarian efforts and international affairs. There is significant material relating to American-U.S.S.R. contacts, particularly in the files on the American-Soviet Friendship Council and the American-Soviet Science Society. There is much, as well, on the impact of the Lysenko controversy in the U. S. Dunn's interest in European scientists can also be seen in the sizable amount of material on the Emergency Committee in Aid of Displaced German Scholars. Material relating to the Kilgore and Magnusson bills for the support of science (predecessors to the NSF) are also in the collection. Of note are data on the following: National Research Council Committee on Experimental Animals and Plants; research on the population study of the Jewish community in Rome; and Columbia University. There is much in the correspondence concerning Drosophila, poultry genetics, and other such topics; Walter Landauer is Dunn's major correspondent.

One of the four horsemen of the evolutionary synthesis of the 1940s, Theodosius Dobzhansky played a crucial role in bridging the gap between theoretical and empirical approaches in genetics and in promoting the Neo-Darwinian synthesis. His contributions to the biological species concept and to an understanding the evolutionary dynamics of wild populations of Drosophila were fundamental to the development of modern population genetics and evolutionary thought. The Dobzhansky Papers are a remnant of the correspondence and writings of the geneticist and evolutionary biologist, Theodosius Dobzhansky. The correspondence (7.5 linear feet) provides insight into Dobzhansky's scientific, philosophical, and social views, particularly during the last decade of his life. Equally valuable are the 54 notebooks (ca.1917-1975) which comprise an almost uninterrupted self-commentary on Dobzhansky's career, replete with typescripts of personal letters and short essays sent to colleagues and friends. The collection also contains two unbound volumes of annotated "reminiscences" from the Columbia Oral History Project, 1962; two bound volumes of papers dedicated to him on his 70th birthday; and 1.5 linear feet of photographs.

The correspondence in this collection concerns behavior genetics, evolution, heredity, etc. There is material relating to the congresses of the Permanent International Committee on Genetics, and the IXth (Bellagio, 1953), Xth (Montreal, 1958), and XIth (The Hague, 1963) International Congress of Genetics. There is also correspondence pertaining to the Cold Spring Harbor Symposium on Quantitative Biology (1955), the Mendel Semi-Centennial Symposium (1950), the Soviet geneticists' visit to the U.S. in 1967, and to Anton R. Zhebrak.

The collection includes three accessions: (1) a portion of Lewontin's correspondence files (mainly A-L) and copies of papers acquired in 1979; (2) a 2003 accession with files on various subjects and correspondence with about 30 colleagues, and (3) a substantial 2018 accession of about 60 linear feet that includes correspondence, manuscripts, and subject files. The topics discussed in the letters are numerous, including much on contemporary scientific controversies such as race, Darwin, evolution, intelligence, and biological determinism.

The geneticist Milislav Demerec emigrated from Yugloslavia in 1919, spending nearly his entire career in the Department of Genetics at Cold Spring Harbor Laboratory. Working initially on the genetics of maize and later on Drosophila virilis, his research interests included radiation and chemical mutagenesis, and during the Second World War, penicillin and the genetics of antibiotic resistance. Demerec served as head of the laboratory at Cold Spring Harbor from 1941 until 1960. The Demerec collection contains the extant professional papers of Milislav Demerec, dating primarily from the time of his arrival at Cold Spring Harbor until his retirement. In addition to his correspondence with colleagues, the collection includes interesting material on the administration of Cold Spring Harbor laboratory during the 1940s and 1950s, data and research notes, material relating to professional organizations (e.g. Genetics Society of America, American Society of Naturalists), a lengthy series of lectures given by Demerec, and a large number of photographs pertaining to Demerec's research, but also to his colleagues and Cold Spring Harbor itself. There is also a Register of visitors to the laboratory (1927-1945) and a Milislav Demerec reprint list.

Between 1968 and 1978, the historian of science Horace Freeland Judson conducted extensive oral history interviews with biochemists and molecular biologists relating to the development of their field. The correspondence, transcripts of interviews, and taped interviews that comprise the Judson collection formed the research material used by Judson in his book, The Eighth Day of Creation (New York, 1979). Permission to quote must be obtained from Dr. Judson and access to some files is restricted.

Sewall Wright ranks among the most influential figures in the field of population genetics during the 20th century, and made important contributions to biostatistics, biometrics, and evolutionary theory. These papers contain much of Wright's professional correspondence, scattered research notes, and drafts of a small number of papers.

The James V. Neel Papers document nearly every phase of the career of one of the founders of human population genetics in the United States. Neel was particularly thorough and organized, and retained virtually all of his significant scientific correspondence, committee reports, minutes of meetings, and drafts of manuscripts. The collection also includes data collected during Neel's work among the Xavante, Yanomanö and other indigenous populations. In a career that spanned the period from the late work of Thomas Hunt Morgan and Charles B. Davenport to the contemporary world of molecular genetics and nucleic acids, Neel knew, worked with, and corresponded with many of the most influential 20th century practitioners of genetics. The collection begins in earnest in 1943, after Neel had decided to focus on human genetics. Neel's work with Drosophila and none of his Drosophila manuscripts are found in the collection.

Founded by the Brooklyn Institute of Arts and Sciences in 1890, the Biological Laboratory at Cold Spring Harbor, N.Y., was little more than a languishing outpost until the arrival of Charles B. Davenport in 1898. Over the course of two decades, the ambitious young biologist used his extraordinary administrative skills to transform the institution into the premier center of eugenical study and, as its director, to position himself as the leading spokesman for eugenical research in North America. The Davenport Papers (ca. 63 lin. feet) is a large and nearly comprehensive body of correspondence, lectures, diaries (1878-1942, mostly brief entries of an uneven character), student notebooks and family correspondence pertaining to Charles Davenport and the Cold Spring Harbor Laboratory. The collection is divided into two series, the Charles Davenport Papers, which provides valuable documentation of the development of American biology, animal and plant genetics, and eugenics during the period 1898-1942, with some perspective on the international eugenics movement. Series II, the Cold Spring Harbor Records (ca.20 lin. feet), consists largely of administrative correspondence relating to the laboratory, including Davenport's correspondence with Carnegie administrators (esp. Robert Woodward and John Merriam), accounts and reports concerning financial matters, publications, salaries, material relative to the early history of Cold Spring Harbor labs, and records relative to the numerous professional assistants who worked under Davenport. Among the major correspondents are the American Breeders Association, Committee on Eugenics; American Eugenics Society; American Society of Naturalists; Committee on a Study of the American Negro; Galton Society (see also the extensive correspondence with William K. Gregory); Eugenics Education Society (see Mrs. S. Gotto correspondence); International Congresses of Eugenics; International Federation of Eugenic Organizations, Committee on Race Crossing; National Committee on Mental Hygiene; National Committee on Prisons and Prison Labor; and the Pan-American Conference on Eugenics and Homiculture. There are correspondence and papers relating to the Station for Experimental Evolution, the Eugenics Record Office, and the Carnegie Institution of Washington, and a substantial series relating to a long-range study of children carried out at Letchworth Village, Thiles, New York. This note is currently under review for revision.

The Papers of Curt Stern include extensive correspondence, lectures (1920s-1970s, 1.5 boxes), autobiographical material, articles, zoological course notes, photographs, etc. Stern's various areas of scientific interest are documented in the collection: the chromosome theory of heredity, role of gene mutation and chromosome rearrangements in evolution, action and interaction of genes during individual development, and particularly his contribution to the development of human genetics as a discipline (centered on his popular and influential book, Principles of Human Genetics, 1949, 1960, 1973). Both his career in Germany and the United States is documented in his correspondence. After studying with T. H. Morgan at Columbia University on a Rockefeller Foundation Fellowship (1924-1926), Stern returned to Richard Goldschmidt's lab at the Kaiser-Wilhelm Institute (1926-1932). There is material of note in the collection concerning this period when Stern helped to establish the cytological basis of crossing over. After a short stay at the California Institute of Technology in 1932, Stern's temporary residence in the U. S. became permanent, and his later career at the University of Rochester, 1933-1947 (Chairman, Department of Zoology) and at the University of California, Berkeley, 1947-1970 (there is abundant material on the Department of Zoology) is covered in the collection. There is other material on: American Association for the Advancement of Science Inter-Society Committee on Science Foundation Legislation, 1946-1947; American Society of Human Genetics (Pres., 1957); Atomic Energy Commission (Advisory Committee for Biology and Medicine, 1950-1955); Genetics (journal); Oak Ridge National Laboratory (Advisory Committee for Biology, 1955-1968); and the Rockefeller Foundation. Stern's correspondence with friends and colleagues in Germany, England, and the U. S., during the 1920s-1930s, is of particular note as it documents not only the developments in genetics and the institutional and administrative networks supporting research, but it also offers general comments and observations on science, Germany, and politics. The photographs (2 boxes) include pictures of many prominent geneticists and scientists.